Buy Trikafta* (elexacaftor/tezacaftor/ivacaftor; ivacaftor)

Trikafta (elexacaftor/tezacaftor/ivacaftor; ivacaftor)* is a medication used for the treatment of cystic fibrosis (CF), indicated for CF patients aged 12 years and older with certain mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene that are responsive to Trikafta based on in vitro data.

This product has 2 different tablets. One tablet contains 3 medications (it is a “multi-drug”): elexacaftor, tezacaftor, and ivacaftor. The other tablet contains only ivacaftor. This product is used to treat cystic fibrosis in certain people (those with an abnormal “CFTR” gene). It may help to improve breathing, reduce the risk of lung infections, and improve weight gain. 

• Medicine Name: Trikafta
• Generic Name: Elexacaftor/Tezacaftor/Ivacaftor and Ivacaftor
• Dosage Form & Strength: Tablets: 100mg/50mg/75mg and 150mg, 50mg/25mg/37.5mg and 75mg
• Manufactured By: Vertex Pharmaceuticals Incorporated.

Trikafta is a combination of ivacaftor, a CFTR potentiator, tezacaftor, and elexacaftor used for the treatment of cystic fibrosis (CF) in patients aged 6 years and older who have at least one F508del mutation in the CFTR gene or a mutation in the CFTR gene that is responsive.

Recommended Dosage: The recommended morning and the evening dose should be taken orally approximately 12 hours apart. Swallow tablets whole. The trikafta tablets should be taken with fat-containing food. Examples of snacks or meals that contain fat are those prepared with oils, or butter or those containing cheeses, eggs, nuts, whole milk, or meats.

Recommended Dosage for Adult and Pediatric Patients aged 6 to less than 12 years weighing less than 30 kgs:

• Morning Dose: Two tablets, each containing elexacaftor 50 mg/tezacaftor 25 mg/ivacaftor 37.5 mg.
• Evening Dose: One tablet of ivacaftor 75 mg

Recommended Dosage for Adult and Pediatric Patients aged 6 to less than 12 years weighing 30 kgs or more:

• Morning Dose: Two tablets, each containing elexacaftor 100 mg/tezacaftor 50 mg/ivacaftor 75 mg
• Evening Dose: One tablet of ivacaftor 150 mg

Recommended Dosage for Adult and Pediatric Patients aged 12 years and older:

• Morning Dose: Two tablets, each containing elexacaftor 100 mg/tezacaftor 50 mg/ivacaftor 75 mg
• Evening Dose: One tablet of ivacaftor 150 mg

In case 6 or less hours have passed since the missed or skipped morning or evening dose, the patient should take the missed dose as promptly as possible and continue on the original schedule.

In case more than 6 hours have passed since:

the missed/skipped morning dose, the patient should take the missed/skipped dose as promptly as possible and should not take the evening dose. The next scheduled morning dose needs to be taken at around the usual time.

the missed/skipped evening dose, the patient should not take the missed/skipped dose. The next scheduled morning dose needs to be taken at around the usual time.

Morning and evening doses must not be taken at the same time.

The medicine is approved by the European Medicines Agency (EMA) under the brand-name Kaftrio. We have it available to order as well. See [Kaftrio (elexacaftor/tezacaftor/ivacaftor; ivacaftor)].

Please note that we have a generic form of edaravone available to order as well. See [Trixacar (elexacaftor/tezacaftor/ivacaftor; ivacaftor)].